Profibrinolytic, Antithrombotic, and Antiinflammatory Effects of an Insulin-Sensitizing Strategy in Patients in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Trial | Zendy

Burton E. Sobel | Zendy; Regina M. Hardison | Zendy; Saul Genuth | Zendy; Maria M. Brooks | Zendy; Robert D. McBane | Zendy; David J. Schneider | Zendy; Richard E. Pratley | Zendy; Kurt Huber | Zendy; Robert Wołk | Zendy; Ashok Krishnaswami | Zendy; Robert L. Frye | Zendy

Open Access

Profibrinolytic, Antithrombotic, and Antiinflammatory Effects of an Insulin-Sensitizing Strategy in Patients in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Trial

Author(s) -

Burton E. Sobel,

Regina M. Hardison,

Saul Genuth,

Maria M. Brooks,

Robert D. McBane,

David J. Schneider,

Richard E. Pratley,

Kurt Huber,

Robert Wołk,

Ashok Krishnaswami,

Robert L. Frye

Publication year - 2011

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.110.014860

Subject(s) - medicine , fibrinolysis , plasminogen activator , fibrinogen , insulin , diabetes mellitus , type 2 diabetes , plasminogen activator inhibitor 1 , coronary artery disease , angioplasty , endocrinology , gastroenterology , cardiology

Effects were compared in patients in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial of 2 mechanistically different strategies for treatment of hyperglycemia, insulin-sensitizing and insulin-providing strategies, on biomarker profiles reflecting the balance between fibrinolysis and thrombosis and the intensity of inflammation implicated in diabetic vasculopathy.

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