Arteriogenic Therapy by Intramyocardial Sustained Delivery of a Novel Growth Factor Combination Prevents Chronic Heart Failure | Zendy

Sébastien Banquet | Zendy; Élodie Gomez | Zendy; Lionel Nicol | Zendy; Florence EdwardsLévy | Zendy; JeanPaul Henry | Zendy; Renhai Cao | Zendy; Damien Schapman | Zendy; Brigitte Dautréaux | Zendy; Françoise Lallemand | Zendy; Fabrice Bauer | Zendy; Yihai Cao | Zendy; Christian Thuillez | Zendy; Paul Mulder | Zendy; Vincent Richard | Zendy; Ebba Bråkenhielm | Zendy

Open Access

Arteriogenic Therapy by Intramyocardial Sustained Delivery of a Novel Growth Factor Combination Prevents Chronic Heart Failure

Author(s) -

Sébastien Banquet,

Élodie Gomez,

Lionel Nicol,

Florence EdwardsLévy,

JeanPaul Henry,

Renhai Cao,

Damien Schapman,

Brigitte Dautréaux,

Françoise Lallemand,

Fabrice Bauer,

Yihai Cao,

Christian Thuillez,

Paul Mulder,

Vincent Richard,

Ebba Bråkenhielm

Publication year - 2011

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.110.010264

Subject(s) - hepatocyte growth factor , medicine , angiogenesis , growth factor , vascular endothelial growth factor , fibroblast growth factor , basic fibroblast growth factor , arteriogenesis , therapeutic angiogenesis , heart failure , neovascularization , fibrosis , endocrinology , cancer research , receptor , vegf receptors

Therapeutic angiogenesis is a promising approach for the treatment of cardiovascular diseases, including myocardial infarction and chronic heart failure. We aimed to improve proangiogenic therapies by identifying novel arteriogenic growth factor combinations, developing injectable delivery systems for spatiotemporally controlled growth factor release, and evaluating functional consequences of targeted intramyocardial growth factor delivery in chronic heart failure.

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