Cardiac Resynchronization Therapy as a Therapeutic Option in Patients With Moderate-Severe Functional Mitral Regurgitation and High Operative Risk | Zendy

Rutger J. van Bommel | Zendy; Nina Ajmone Marsan | Zendy; Victoria Delgado | Zendy; C. Jan Willem Borleffs | Zendy; Eva P.M. van Rijnsoever | Zendy; Martin J. Schalij | Zendy; Jeroen J. Bax | Zendy

Open Access

Cardiac Resynchronization Therapy as a Therapeutic Option in Patients With Moderate-Severe Functional Mitral Regurgitation and High Operative Risk

Author(s) -

Rutger J. van Bommel,

Nina Ajmone Marsan,

Victoria Delgado,

C. Jan Willem Borleffs,

Eva P.M. van Rijnsoever,

Martin J. Schalij,

Jeroen J. Bax

Publication year - 2011

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.110.009803

Subject(s) - medicine , functional mitral regurgitation , cardiac resynchronization therapy , mitral regurgitation , heart failure , cardiology , surgery , ejection fraction

Functional mitral regurgitation (MR) is a common finding in heart failure patients with dilated cardiomyopathy and has important prognostic implications. However, the increased operative risk of these patients may result in low referral or high denial rate for mitral valve surgery. Cardiac resynchronization therapy (CRT) has been shown to have a favorable effect on MR. Aims of this study were to (1) evaluate CRT as a therapeutic option in heart failure patients with functional MR and high operative risk and (2) investigate the effect of MR improvement after CRT on prognosis.

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