Protein Kinase D2 Controls Cardiac Valve Formation in Zebrafish by Regulating Histone Deacetylase 5 Activity | Zendy

Steffen Just | Zendy; Ina M. Berger | Zendy; Benjamin Meder | Zendy; Johannes Backs | Zendy; Andreas Keller | Zendy; Sabine Marquart | Zendy; Karen Frese | Zendy; Eva Patzel | Zendy; Gerd-Jörg Rauch | Zendy; Hugo A. Katus | Zendy; Wolfgang Rottbauer | Zendy

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Protein Kinase D2 Controls Cardiac Valve Formation in Zebrafish by Regulating Histone Deacetylase 5 Activity

Author(s) -

Steffen Just,

Ina M. Berger,

Benjamin Meder,

Johannes Backs,

Andreas Keller,

Sabine Marquart,

Karen Frese,

Eva Patzel,

Gerd-Jörg Rauch,

Hugo A. Katus,

Wolfgang Rottbauer

Publication year - 2011

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.110.003301

Subject(s) - histone deacetylase , zebrafish , histone deacetylase 5 , microbiology and biotechnology , hdac1 , notch signaling pathway , histone deacetylase 2 , cancer research , biology , medicine , histone , signal transduction , genetics , gene

The molecular mechanisms that guide heart valve formation are not well understood. However, elucidation of the genetic basis of congenital heart disease is one of the prerequisites for the development of tissue-engineered heart valves.

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