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Intracoronary Versus Intravenous Administration of Abciximab in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention With Thrombus Aspiration
Author(s) -
Youlan L. Gu,
Marthe A. Kampinga,
Wouter G. Wieringa,
Marieke L. Fokkema,
Maarten W. Nijsten,
Hans L. Hillege,
Ad F.M. van den Heuvel,
EngShiong Tan,
Gabija Pundziūtė,
Rik van der Werf,
Siyrous Hoseyni Guyomi,
Iwan C.C. van der Horst,
Felix Zijlstra,
Bart J.G.L. de Smet
Publication year - 2010
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.110.002741
Subject(s) - medicine , abciximab , percutaneous coronary intervention , myocardial infarction , cardiology , st segment , coronary thrombosis , clopidogrel , anesthesia
administration of the glycoprotein IIb/IIIa inhibitor abciximab is an effective adjunctive treatment strategy during primary percutaneous coronary intervention for ST-segment elevation myocardial infarction. Although small-scale studies have suggested beneficial effects of intracoronary over intravenous administration of abciximab, this has not been investigated in a medium-scale randomized clinical trial.

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