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Homocysteine-Lowering and Cardiovascular Disease Outcomes in Kidney Transplant Recipients
Author(s) -
Andrew G. Bostom,
Myra A. Carpenter,
John W. Kusek,
Andrew S. Levey,
Lawrence G. Hunsicker,
Marc A. Pfeffer,
Jacob Selhub,
Paul F. Jacques,
Edward Cole,
Lisa GravensMueller,
Andrew A. House,
Clifton E. Kew,
Joyce L. McKenney,
Álvaro PachecoSilva,
Todd E. Pesavento,
John D. Pirsch,
S. Stephen,
Scott D. Solomon,
Jiang He
Publication year - 2011
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.110.000588
Subject(s) - medicine , kidney disease , homocysteine , dialysis , stroke (engine) , coronary artery disease , multivitamin , risk factor , cardiology , myocardial infarction , surgery , gastroenterology , vitamin , mechanical engineering , engineering
Kidney transplant recipients, like other patients with chronic kidney disease, experience excess risk of cardiovascular disease and elevated total homocysteine concentrations. Observational studies of patients with chronic kidney disease suggest increased homocysteine is a risk factor for cardiovascular disease. The impact of lowering total homocysteine levels in kidney transplant recipients is unknown.

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