Reversal of Severe Heart Failure With a Continuous-Flow Left Ventricular Assist Device and Pharmacological Therapy | Zendy

Emma J. Birks | Zendy; Robert S. George | Zendy; M. Hedger | Zendy; Toufan Bahrami | Zendy; P. Wilton | Zendy; Christopher T. Bowles | Zendy; Carole Webb | Zendy; Robert Bougard | Zendy; Mohammed Amrani | Zendy; Magdi H. Yacoub | Zendy; Gilles Dreyfus | Zendy; Asghar Khaghani | Zendy

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Reversal of Severe Heart Failure With a Continuous-Flow Left Ventricular Assist Device and Pharmacological Therapy

Author(s) -

Emma J. Birks,

Robert S. George,

M. Hedger,

Toufan Bahrami,

P. Wilton,

Christopher T. Bowles,

Carole Webb,

Robert Bougard,

Mohammed Amrani,

Magdi H. Yacoub,

Gilles Dreyfus,

Asghar Khaghani

Publication year - 2011

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.109.933960

Subject(s) - medicine , heart failure , ejection fraction , ventricular assist device , cardiology , pulmonary wedge pressure , inotrope , dilated cardiomyopathy , cardiac index , extracorporeal membrane oxygenation , myocardial infarction , hemodynamics , cardiac output

We have previously shown that a specific combination of drug therapy and left ventricular assist device unloading results in significant myocardial recovery, sufficient to allow pump removal, in two thirds of patients with dilated cardiomyopathy receiving a Heartmate I pulsatile device. However, this protocol has not been used with nonpulsatile devices.

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