Mechanism of Beneficial Effects of Restrictive Mitral Annuloplasty in Patients With Dilated Cardiomyopathy and Functional Mitral Regurgitation | Zendy

Koji Takeda | Zendy; Kazuhiro Taniguchi | Zendy; Yasuhiro Shudo | Zendy; Satoshi Kainuma | Zendy; Seiki Hamada | Zendy; Hajime Matsue | Zendy; Goro Matsumiya | Zendy; Yoshiki Sawa | Zendy

Open Access

Mechanism of Beneficial Effects of Restrictive Mitral Annuloplasty in Patients With Dilated Cardiomyopathy and Functional Mitral Regurgitation

Author(s) -

Koji Takeda,

Kazuhiro Taniguchi,

Yasuhiro Shudo,

Satoshi Kainuma,

Seiki Hamada,

Hajime Matsue,

Goro Matsumiya,

Yoshiki Sawa

Publication year - 2010

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.109.927855

Subject(s) - medicine , functional mitral regurgitation , dilated cardiomyopathy , cardiology , mitral regurgitation , mechanism (biology) , heart failure , ejection fraction , philosophy , epistemology

Restrictive mitral annuloplasty (RMA) often leads to reverse left ventricular (LV) remodeling in patients with advanced cardiomyopathy and functional mitral regurgitation. However, the mechanism responsible for its favorable effects on LV ejection performance has been poorly understood. We evaluated systolic wall stress using cineangiographic multidetector computed tomography (MDCT) and our developed software system to assess stress-shortening relations before and after RMA.

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