Regression of Myocardial Hypertrophy After Aortic Valve Replacement | Zendy

George Petrov | Zendy; Vera RegitzZagrosek | Zendy; Elke Lehmkuhl | Zendy; Thomas Krabatsch | Zendy; Anne Dunkel | Zendy; Michael Dandel | Zendy; Elke Dworatzek | Zendy; Shokoufeh Mahmoodzadeh | Zendy; Carola Schubert | Zendy; Eva Becher | Zendy; H. Hampl | Zendy; Roland Hetzer | Zendy

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Regression of Myocardial Hypertrophy After Aortic Valve Replacement

Author(s) -

George Petrov,

Vera RegitzZagrosek,

Elke Lehmkuhl,

Thomas Krabatsch,

Anne Dunkel,

Michael Dandel,

Elke Dworatzek,

Shokoufeh Mahmoodzadeh,

Carola Schubert,

Eva Becher,

H. Hampl,

Roland Hetzer

Publication year - 2010

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.109.927764

Subject(s) - medicine , muscle hypertrophy , pressure overload , fibrosis , ejection fraction , cardiology , aortic valve replacement , myocardial fibrosis , left ventricular hypertrophy , stenosis , aortic valve stenosis , endocrinology , blood pressure , heart failure , cardiac hypertrophy

In patients with aortic stenosis, pressure overload induces cardiac hypertrophy and fibrosis. Female sex and estrogens influence cardiac remodeling and fibrosis in animal models and in men. Sex differences and their molecular mechanisms in hypertrophy regression after aortic valve replacement have not yet been studied.

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