Alteration of Parasympathetic/Sympathetic Ratio in the Infarcted Myocardium After Schwann Cell Transplantation Modified Electrophysiological Function of Heart | Zendy

Hao Zhang | Zendy; Xin Yuan | Zendy; Peifeng Jin | Zendy; Jianfeng Hou | Zendy; Wei Wang | Zendy; Yingjie Wei | Zendy; Shengshou Hu | Zendy

Open Access

Alteration of Parasympathetic/Sympathetic Ratio in the Infarcted Myocardium After Schwann Cell Transplantation Modified Electrophysiological Function of Heart

Author(s) -

Hao Zhang,

Xin Yuan,

Peifeng Jin,

Jianfeng Hou,

Wei Wang,

Yingjie Wei,

Shengshou Hu

Publication year - 2010

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.109.922740

Subject(s) - medicine , transplantation , cardiology , autonomic nervous system , heart transplantation , myocardial infarction , heart rate , blood pressure

Neural remodeling after myocardial infarction (MI) may cause fatal ventricular arrhythmia. Schwann cells (SCs), which are important for neurogenesis, are dramatically reduced after MI. We investigated the feasibility of modifying nervous system regeneration after MI and the efficacy by which it may prevent ventricular arrhythmia following SC transplantation.

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