Open AccessSelective Molecular Potassium Channel Blockade Prevents Atrial Fibrillation
Author(s) -
Guy Amit,
Kan Kikuchi,
Ian D. Greener,
Lizhu Yang,
Victor Novack,
J. Kevin Donahue
Publication year - 2010
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.109.911156
Subject(s) - medicine , atrial fibrillation , blockade , potassium channel , cardiology , potassium channel blocker , pharmacology , receptor
Safety and efficacy limit currently available atrial fibrillation (AF) therapies. We hypothesized that atrial gene transfer would allow focal manipulation of atrial electrophysiology and, by eliminating reentry, would prevent AF.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom