Effect of Nonuniform Muscle Contraction on Sustainability and Frequency of Triggered Arrhythmias in Rat Cardiac Muscle | Zendy

Makoto Miura | Zendy; Taichi Nishio | Zendy; Taiki Hattori | Zendy; Naomi Murai | Zendy; Bruno D. Stuyvers | Zendy; Chiyohiko Shindoh | Zendy; Penelope A. Boyden | Zendy

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Effect of Nonuniform Muscle Contraction on Sustainability and Frequency of Triggered Arrhythmias in Rat Cardiac Muscle

Author(s) -

Makoto Miura,

Taichi Nishio,

Taiki Hattori,

Naomi Murai,

Bruno D. Stuyvers,

Chiyohiko Shindoh,

Penelope A. Boyden

Publication year - 2010

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.109.907717

Subject(s) - contraction (grammar) , medicine , muscle contraction , cardiac muscle , membrane potential , cardiac cycle , myofilament , endocrinology , biophysics , cardiology , myocyte , biology

Arrhythmias are benign or lethal, depending on their sustainability and frequency. To determine why lethal arrhythmias are prone to occur in diseased hearts, usually characterized by nonuniform muscle contraction, we investigated the effect of nonuniformity on sustainability and frequency of triggered arrhythmias.

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