Risk of Recurrent Venous Thrombosis in Homozygous Carriers and Double Heterozygous Carriers of Factor V Leiden and Prothrombin G20210A
Author(s) -
Willem M. Lijfering,
Saskia Middeldorp,
Nic J.G.M. Veeger,
Karly Hamulyák,
Martin H. Prins,
Harry R. Büller,
Jan van der Meer
Publication year - 2010
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.109.906347
Subject(s) - factor v leiden , medicine , prothrombin g20210a , risk factor , loss of heterozygosity , venous thrombosis , thrombophilia , gastroenterology , factor v , confidence interval , thrombosis , genetics , allele , biology , gene
Homozygous or double heterozygous factor V Leiden and/or prothrombin G20210A is a rare inherited thrombophilic trait. Whether individuals with this genetic background have an increased risk of recurrent venous thrombosis is uncertain.
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