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Natural History of Experimental Coronary Atherosclerosis and Vascular Remodeling in Relation to Endothelial Shear Stress
Author(s) -
Konstantinos C. Koskinas,
Charles L. Feldman,
Yiannis S. Chatzizisis,
Ahmet U. Coskun,
Michael Jonas,
Charles Maynard,
Aaron B. Baker,
Michail I. Papafaklis,
Elazer R. Edelman,
Peter H. Stone
Publication year - 2010
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.109.901678
Subject(s) - medicine , intravascular ultrasound , coronary atherosclerosis , hyperlipidemia , natural history , cardiology , coronary arteries , inflammation , in vivo , vascular remodelling in the embryo , hemodynamics , ventricular remodeling , fibrous cap , pathology , diabetes mellitus , artery , heart failure , coronary artery disease , endocrinology , microbiology and biotechnology , biology
The natural history of heterogeneous atherosclerotic plaques and the role of local hemodynamic factors throughout their development are unknown. We performed a serial study to assess the role of endothelial shear stress (ESS) and vascular remodeling in the natural history of coronary atherosclerosis.

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