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Tumor Necrosis Factor Receptor–Associated Factor 1 (TRAF1) Deficiency Attenuates Atherosclerosis in Mice by Impairing Monocyte Recruitment to the Vessel Wall
Author(s) -
Anna Missiou,
Natascha Köstlin,
Nerea Varo,
Philipp Rudolf,
Peter Aichele,
Sandra Ernst,
Christian Münkel,
Carina Walter,
Peter Stachon,
Benjamin Sommer,
Dietmar Pfeifer,
Katja Zirlik,
Lindsey A. MacFarlane,
Dennis Wolf,
Erdyni N. Tsitsikov,
Christoph Bode,
Peter Libby,
Andreas Zirlik
Publication year - 2010
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.109.895037
Subject(s) - tumor necrosis factor alpha , medicine , tumor necrosis factor receptor 1 , cell adhesion molecule , monocyte , endothelium , inflammation , intercellular adhesion molecule , intercellular adhesion molecule 1 , immunology , cancer research , cell adhesion , endocrinology , biology , cell , genetics , tumor necrosis factor receptor
Members of the tumor necrosis factor superfamily, such as tumor necrosis factor-alpha, potently promote atherogenesis in mice and humans. Tumor necrosis factor receptor-associated factors (TRAFs) are cytoplasmic adaptor proteins for this group of cytokines.

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