Circulating Endothelial Progenitor Cells Do Not Contribute to Plaque Endothelium in Murine Atherosclerosis | Zendy

Mette K. Hagensen | Zendy; Jeong Shim | Zendy; Troels Thim | Zendy; Erling Falk | Zendy; Jacob Fog Bentzon | Zendy

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Circulating Endothelial Progenitor Cells Do Not Contribute to Plaque Endothelium in Murine Atherosclerosis

Author(s) -

Mette K. Hagensen,

Jeong Shim,

Troels Thim,

Erling Falk,

Jacob Fog Bentzon

Publication year - 2010

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.109.885459

Subject(s) - medicine , progenitor cell , endothelium , endothelial stem cell , endothelial progenitor cell , progenitor , stem cell , microbiology and biotechnology , in vitro , biology , biochemistry

It has been reported that circulating endothelial progenitor cells (EPCs) home to and differentiate into endothelial cells after various kinds of arterial injury. By inference, EPCs are also proposed to be important in the most important arterial disease, atherosclerosis, but the evidence for this theory is not clear. In the present study, we assessed the contribution of circulating EPCs to plaque endothelium in apolipoprotein E-deficient (apoE(-/-)) mice.

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