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Effect of Rosiglitazone on Progression of Coronary Atherosclerosis in Patients With Type 2 Diabetes Mellitus and Coronary Artery Disease
Author(s) -
Hertzel C. Gerstein,
Robert E. Ratner,
Christopher P. Can,
Patrick W. Serruys,
Hector Garcia-Garcia,
GerritAnne van Es,
Nikheel S. Kolatkar,
Barbara G. Kravitz,
Diane Miller,
Chun Huang,
Peter J. Fitzgerald,
Richard W. Nesto
Publication year - 2010
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.109.881003
Subject(s) - medicine , rosiglitazone , cardiology , coronary artery disease , diabetes mellitus , coronary atherosclerosis , type 2 diabetes mellitus , coronary heart disease , disease , endocrinology
Rosiglitazone has several properties that may affect progression of atherosclerosis. The Assessment on the Prevention of Progression by Rosiglitazone on Atherosclerosis in Diabetes Patients With Cardiovascular History (APPROACH) study was undertaken to determine the effect of the thiazolidinedione rosiglitazone on coronary atherosclerosis as assessed by intravascular ultrasound compared with the sulfonylurea glipizide.

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