Open AccessA Common Variant at 9p21 Is Associated With Sudden and Arrhythmic Cardiac Death
Author(s) -
Christopher NewtonCheh,
Nancy R. Cook,
Martin VanDenburgh,
Eric B. Rimm,
Paul M. Ridker,
Christine M. Albert
Publication year - 2009
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.109.879049
Subject(s) - medicine , odds ratio , sudden cardiac death , prospective cohort study , myocardial infarction , confidence interval , coronary artery disease , cardiology , sudden death
Although a heritable basis for sudden cardiac death (SCD) is suggested by the impact of family history on SCD risk, common genetic determinants have been difficult to identify. We hypothesized that a common variant at chromosome 9p21 related to myocardial infarction would influence SCD risk.
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