Augmentation of Left Ventricular Contractility by Cardiac Sympathetic Neural Stimulation | Zendy

Christian Meyer | Zendy; Obaida R. Rana | Zendy; Erol Saygili | Zendy; Christopher Gemein | Zendy; Michael Becker | Zendy; Kay Nolte | Zendy; Joachim Weis | Zendy; Thomas Schimpf | Zendy; Christian Knackstedt | Zendy; Karl Mischke | Zendy; Rainer Hoffmann | Zendy; Malte Kelm | Zendy; Dainius H. Pauža | Zendy; Patrick Schauerte | Zendy

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Augmentation of Left Ventricular Contractility by Cardiac Sympathetic Neural Stimulation

Author(s) -

Christian Meyer,

Obaida R. Rana,

Erol Saygili,

Christopher Gemein,

Michael Becker,

Kay Nolte,

Joachim Weis,

Thomas Schimpf,

Christian Knackstedt,

Karl Mischke,

Rainer Hoffmann,

Malte Kelm,

Dainius H. Pauža,

Patrick Schauerte

Publication year - 2010

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.109.874263

Subject(s) - medicine , contractility , cardiology , stimulation , sympathetic nervous system , sympathetic innervation , blood pressure

Electric stimulation of mediastinal sympathetic cardiac nerves increases cardiac contractility but is not selective for the left ventricle because it elicits sinus tachycardia and enhanced atrioventricular conduction. The aim of this study was to identify sympathetic neural structures inside the heart that selectively control left ventricular inotropy and can be accessed by transvenous catheter stimulation.

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