Cardiomyocyte Differentiation of Human Induced Pluripotent Stem Cells | Zendy

Limor Zwi | Zendy; Oren Caspi | Zendy; Gil Arbel | Zendy; Irit Huber | Zendy; Amira Gepstein | Zendy; InHyun Park | Zendy; Lior Gepstein | Zendy

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Cardiomyocyte Differentiation of Human Induced Pluripotent Stem Cells

Author(s) -

Limor Zwi,

Oren Caspi,

Gil Arbel,

Irit Huber,

Amira Gepstein,

InHyun Park,

Lior Gepstein

Publication year - 2009

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.109.868885

Subject(s) - embryoid body , induced pluripotent stem cell , microbiology and biotechnology , embryonic stem cell , medicine , cellular differentiation , myocyte , stem cell , reprogramming , biology , cell , genetics , gene

The ability to derive human induced pluripotent stem (hiPS) cell lines by reprogramming of adult fibroblasts with a set of transcription factors offers unique opportunities for basic and translational cardiovascular research. In the present study, we aimed to characterize the cardiomyocyte differentiation potential of hiPS cells and to study the molecular, structural, and functional properties of the generated hiPS-derived cardiomyocytes.

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