Integrative Predictive Model of Coronary Artery Calcification in Atherosclerosis
Author(s) -
Michael J. McGeachie,
Rachel L. Badovinac Ramoni,
Josyf C. Mychaleckyj,
Karen L. Furie,
Jonathan M. Dreyfuss,
Yongmei Liu,
David M. Herrington,
Xiuqing Guo,
João A.C. Lima,
Wendy S. Post,
Jerome I. Rotter,
Stephen S. Rich,
Michèle M. Sale,
Marco Ramoni
Publication year - 2009
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.109.865501
Subject(s) - medicine , cardiology , coronary artery disease , calcification , coronary atherosclerosis , artery
Many different genetic and clinical factors have been identified as causes or contributors to atherosclerosis. We present a model of preclinical atherosclerosis based on genetic and clinical data that predicts the presence of coronary artery calcification in healthy Americans of European descent 45 to 84 years of age in the Multi-Ethnic Study of Atherosclerosis (MESA).
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