Repair of Acute Myocardial Infarction by Human Stemness Factors Induced Pluripotent Stem Cells | Zendy

Timothy J. Nelson | Zendy; Almudena MartinezFernandez | Zendy; Satsuki Yamada | Zendy; Carmen Pérez-Terzic | Zendy; Yasuhiro Ikeda | Zendy; André Terzic | Zendy

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Repair of Acute Myocardial Infarction by Human Stemness Factors Induced Pluripotent Stem Cells

Author(s) -

Timothy J. Nelson,

Almudena MartinezFernandez,

Satsuki Yamada,

Carmen Pérez-Terzic,

Yasuhiro Ikeda,

André Terzic

Publication year - 2009

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.109.865154

Subject(s) - induced pluripotent stem cell , reprogramming , sox2 , embryonic stem cell , stem cell , klf4 , medicine , microbiology and biotechnology , regenerative medicine , biology , immunology , cell , genetics , gene

Nuclear reprogramming provides an emerging strategy to produce embryo-independent pluripotent stem cells from somatic tissue. Induced pluripotent stem cells (iPS) demonstrate aptitude for de novo cardiac differentiation, yet their potential for heart disease therapy has not been tested.

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