Significant Changes in Mitral Valve Leaflet Matrix Composition and Turnover With Tachycardia-Induced Cardiomyopathy | Zendy

Elizabeth H. Stephens | Zendy; Tomasz A. Timek | Zendy; George T. Daughters | Zendy; Joyce J. Kuo | Zendy; Aaron M. Patton | Zendy; L. Scott Baggett | Zendy; Neil B. Ingels | Zendy; D. Craig Miller | Zendy; K. Jane GrandeAllen | Zendy

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Significant Changes in Mitral Valve Leaflet Matrix Composition and Turnover With Tachycardia-Induced Cardiomyopathy

Author(s) -

Elizabeth H. Stephens,

Tomasz A. Timek,

George T. Daughters,

Joyce J. Kuo,

Aaron M. Patton,

L. Scott Baggett,

Neil B. Ingels,

D. Craig Miller,

K. Jane GrandeAllen

Publication year - 2009

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.108.844159

Subject(s) - medicine , cardiology , mitral valve , cardiomyopathy , extracellular matrix , leaflet (botany) , ventricular remodeling , ejection fraction , anatomy , heart failure , microbiology and biotechnology , biology , paleontology

Dilated cardiomyopathy (DCM) involves significant remodeling of the left ventricular-mitral valve (MV) complex, but little is known regarding the remodeling of the mitral leaflets. The aim of this study was to assess changes in matrix composition and turnover in MV leaflets with DCM.

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