Glycome and Transcriptome Regulation of Vasculogenesis
Author(s) -
Rania Harfouche,
Dirk M. Hentschel,
Stephanie Piecewicz,
Sudipta Basu,
Cristin G. Print,
David A. Eavarone,
Tanyel Kiziltepe,
Ram Sasisekharan,
Shiladitya Sengupta
Publication year - 2009
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.108.837724
Subject(s) - vasculogenesis , microbiology and biotechnology , zebrafish , embryonic stem cell , heparan sulfate , biology , gene knockdown , transcriptome , stem cell , cellular differentiation , matrigel , glycosaminoglycan , cell , biochemistry , progenitor cell , cell culture , genetics , gene expression , gene
Therapeutic vasculogenesis is an emerging concept that can potentially be harnessed for the management of ischemic pathologies. The present study elucidates the potential coregulation of vasculogenesis by the heparan sulfate glycosaminoglycan-rich cell-surface glycome and the transcriptome.
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