Macrophage-Specific Expression of Mannose-Binding Lectin Controls Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice | Zendy

Robert A. Matthijsen | Zendy; Menno P.J. de Winther | Zendy; Dian Kuipers | Zendy; Ingeborg van der Made | Zendy; Christian Weber | Zendy; M. Verónica Herías | Zendy; Marion J. Gijbels | Zendy; Wim A. Buurman | Zendy

Open Access

Macrophage-Specific Expression of Mannose-Binding Lectin Controls Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice

Author(s) -

Robert A. Matthijsen,

Menno P.J. de Winther,

Dian Kuipers,

Ingeborg van der Made,

Christian Weber,

M. Verónica Herías,

Marion J. Gijbels,

Wim A. Buurman

Publication year - 2009

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.108.830661

Subject(s) - mannan binding lectin , medicine , macrophage , lectin , mannose receptor , receptor , lipoprotein , foam cell , scavenger receptor , microbiology and biotechnology , immunology , biochemistry , cholesterol , biology , in vitro

With consideration of the central role of the innate immune system in atherogenesis and mannose-binding lectin (MBL) as an innate regulator of immunity, the role of MBL in experimental and human atherosclerosis was assessed.

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