MicroRNA-320 Is Involved in the Regulation of Cardiac Ischemia/Reperfusion Injury by Targeting Heat-Shock Protein 20
Author(s) -
Xiao-Ping Ren,
Jinghai Wu,
Xiaohong Wang,
Maureen A. Sartor,
Qian Jiang,
Keith Jones,
Persoulla Nicolaou,
Tracy J. Pritchard,
GuoChang Fan
Publication year - 2009
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.108.814145
Subject(s) - antagomir , gene knockdown , ex vivo , microrna , in vivo , heat shock protein , cardioprotection , luciferase , medicine , reperfusion injury , apoptosis , microbiology and biotechnology , ischemia , biology , transfection , gene , biochemistry , genetics
Recent studies have identified critical roles for microRNAs (miRNAs) in a variety of cellular processes, including regulation of cardiomyocyte death. However, the signature of miRNA expression and possible roles of miRNA in the ischemic heart have been less well studied.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom