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MicroRNA-320 Is Involved in the Regulation of Cardiac Ischemia/Reperfusion Injury by Targeting Heat-Shock Protein 20
Author(s) -
Xiao-Ping Ren,
Jinghai Wu,
Xiaohong Wang,
Maureen A. Sartor,
Qian Jiang,
Keith Jones,
Persoulla Nicolaou,
Tracy J. Pritchard,
GuoChang Fan
Publication year - 2009
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.108.814145
Subject(s) - antagomir , gene knockdown , ex vivo , microrna , in vivo , heat shock protein , cardioprotection , luciferase , medicine , reperfusion injury , apoptosis , microbiology and biotechnology , ischemia , biology , transfection , gene , biochemistry , genetics
Recent studies have identified critical roles for microRNAs (miRNAs) in a variety of cellular processes, including regulation of cardiomyocyte death. However, the signature of miRNA expression and possible roles of miRNA in the ischemic heart have been less well studied.

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