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Cardiovascular Death and Nonfatal Myocardial Infarction in Acute Coronary Syndrome Patients Receiving Coronary Stenting Are Predicted by Residual Platelet Reactivity to ADP Detected by a Point-of-Care Assay
Author(s) -
Rossella Marcucci,
Anna Maria Gori,
Rita Paniccia,
Betti Giusti,
Serafina Valente,
Cristina Giglioli,
Piergiovanni Buonamici,
David Antoniucci,
Rosanna Abbate,
Gian Franco Gensini
Publication year - 2009
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.108.812636
Subject(s) - medicine , clopidogrel , percutaneous coronary intervention , cardiology , acute coronary syndrome , myocardial infarction , p2y12 , aspirin , ejection fraction , stent , conventional pci , heart failure
The clinical impact of platelet aggregation assessed by point-of-care assays is unknown. We sought to evaluate whether high residual platelet reactivity (RPR) to ADP during clopidogrel therapy, measured by a point-of-care assay, predicts adverse clinical events in acute coronary syndrome patients undergoing percutaneous coronary intervention.

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