Circulating Endothelial Cells | Zendy

David M. Smadja | Zendy; Pascale Gaussem | Zendy; Laëtitia Mauge | Zendy; Dominique Israëł-Biet | Zendy; Françoise DignatGeorge | Zendy; Séverine Peyrard | Zendy; Gabriella Agnoletti | Zendy; Pascal Vouhé | Zendy; Damien Bonnet | Zendy; Marilyne Lévy | Zendy

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Circulating Endothelial Cells

Author(s) -

David M. Smadja,

Pascale Gaussem,

Laëtitia Mauge,

Dominique Israëł-Biet,

Françoise DignatGeorge,

Séverine Peyrard,

Gabriella Agnoletti,

Pascal Vouhé,

Damien Bonnet,

Marilyne Lévy

Publication year - 2009

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.108.808246

Subject(s) - medicine , cd146 , progenitor cell , heart disease , lung , cd34 , endothelium , endothelial dysfunction , cardiology , biopsy , pulmonary artery , lung biopsy , pathology , circulatory system , endothelial progenitor cell , gastroenterology , stem cell , genetics , biology

Congenital heart disease can be complicated by pulmonary arterial hypertension (PAH), the reversibility of which is often difficult to predict. We recently reported a lung biopsy study showing impaired apoptotic regulation of endothelial cells in irreversible PAH. The objective of the present study was to identify noninvasive biomarkers of endothelial turnover that could be used to identify congenital heart disease patients at risk of irreversible PAH.

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