Randomized Comparison of Everolimus-Eluting and Paclitaxel-Eluting Stents | Zendy

Gregg W. Stone | Zendy; Mark Midei | Zendy; William Newman | Zendy; Mark Sanz | Zendy; James Hermiller | Zendy; Jerome Williams | Zendy; Naim Farhat | Zendy; Ronald Caputo | Zendy; Nicholas Xenopoulos | Zendy; Robert J. Applegate | Zendy; Paul Gordon | Zendy; Roseann White | Zendy; Krishnankutty Sudhir | Zendy; Donald E. Cutlip | Zendy; John L. Petersen | Zendy

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Randomized Comparison of Everolimus-Eluting and Paclitaxel-Eluting Stents

Author(s) -

Gregg W. Stone,

Mark Midei,

William Newman,

Mark Sanz,

James Hermiller,

Jerome Williams,

Naim Farhat,

Ronald Caputo,

Nicholas Xenopoulos,

Robert J. Applegate,

Paul Gordon,

Roseann White,

Krishnankutty Sudhir,

Donald E. Cutlip,

John L. Petersen

Publication year - 2009

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.108.803528

Subject(s) - medicine , myocardial infarction , hazard ratio , stent , everolimus , cardiology , target lesion , coronary artery disease , revascularization , percutaneous coronary intervention , confidence interval

In the prospective randomized Clinical Evaluation of the Xience V Everolimus Eluting Coronary Stent System in the Treatment of Patients with de novo Native Coronary Artery Lesions (SPIRIT) III trial, an everolimus-eluting stent (EES) compared with a widely used paclitaxel-eluting stent (PES) resulted in a statistically significant reduction in angiographic in-segment late loss at 8 months and noninferior rates of target vessel failure (cardiac death, myocardial infarction, or target vessel revascularization) at 1 year. The safety and efficacy of EES after 1 year have not been reported.

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