Collagen-Targeting Vascular Endothelial Growth Factor Improves Cardiac Performance After Myocardial Infarction | Zendy

Jing Zhang | Zendy; Liang Ding | Zendy; Yannan Zhao | Zendy; Wenjie Sun | Zendy; Chen Bing | Zendy; Hang Lin | Zendy; Xia Wang | Zendy; Lujie Zhang | Zendy; Biao Xu | Zendy; Jianwu Dai | Zendy

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Collagen-Targeting Vascular Endothelial Growth Factor Improves Cardiac Performance After Myocardial Infarction

Author(s) -

Jing Zhang,

Liang Ding,

Yannan Zhao,

Wenjie Sun,

Chen Bing,

Hang Lin,

Xia Wang,

Lujie Zhang,

Biao Xu,

Jianwu Dai

Publication year - 2009

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.108.800565

Subject(s) - medicine , myocardial infarction , cardiology , vascular endothelial growth factor , growth factor , vegf receptors , receptor

Vascular endothelial growth factor (VEGF) is an important active protein for the induction of angiogenesis and improvement in cardiac function after myocardial ischemia; however, the lack of a delivery system targeted to the injured myocardium reduces the local therapeutic efficacy of VEGF and increases its possible adverse effects.

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