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Mechanisms of Aortic and Cardiac Dysfunction in Uremic Mice With Aortic Calcification
Author(s) -
Julien Maizel,
Isabelle Six,
Michel Slama,
Christophe Tribouilloy,
H Sevestre,
Sabrina Poirot,
Philippe Giummelly,
Jeffrey Atkinson,
Gabriel Choukroun,
Michel Andréjak,
Saı̈d Kamel,
J.C. Mazière,
Ziad A. Massy
Publication year - 2009
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.108.797407
Subject(s) - medicine , aorta , calcification , apolipoprotein b , cardiology , left ventricular hypertrophy , endothelial dysfunction , endocrinology , diastole , blood pressure , cholesterol
Chronic renal failure (CRF) is associated with cardiac dysfunction and increased aortic stiffness. The mechanisms involved are not clearly understood. We examined changes over time in cardiac and aortic function in a murine CRF model.

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