Multipotent Mesenchymal Stem Cells Acquire a Lymphendothelial Phenotype and Enhance Lymphatic Regeneration In Vivo
Author(s) -
Claudius Conrad,
Hanno Nieß,
Ralf Huss,
Stephan Huber,
Irene von Luettichau,
Peter J. Nelson,
Harald C. Ott,
Karl-Walter Jauch,
Christiane J. Bruns
Publication year - 2009
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.108.793208
Subject(s) - mesenchymal stem cell , medicine , regeneration (biology) , lymphatic system , phenotype , multipotent stem cell , stem cell , in vivo , microbiology and biotechnology , pathology , biology , progenitor cell , gene , genetics
The importance and therapeutic value of stem cells in lymphangiogenesis are poorly understood. We evaluated the potential of human and murine mesenchymal stem cells (MSCs) to acquire a lymphatic phenotype in vitro and to enhance lymphatic regeneration in vivo.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom