Adenosine A 3 Receptor Deficiency Exerts Unanticipated Protective Effects on the Pressure-Overloaded Left Ventricle | Zendy

Zhongbing Lu | Zendy; John Fassett | Zendy; Xin Xu | Zendy; Xinli Hu | Zendy; Guangshuo Zhu | Zendy; Joel P. French | Zendy; Ping Zhang | Zendy; Jürgen Schnermann | Zendy; Robert J. Bache | Zendy; Yingjie Chen | Zendy

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Adenosine A ₃ Receptor Deficiency Exerts Unanticipated Protective Effects on the Pressure-Overloaded Left Ventricle

Author(s) -

Zhongbing Lu,

John Fassett,

Xin Xu,

Xinli Hu,

Guangshuo Zhu,

Joel P. French,

Ping Zhang,

Jürgen Schnermann,

Robert J. Bache,

Yingjie Chen

Publication year - 2008

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.108.788307

Subject(s) - medicine , endocrinology , adenosine , nitrotyrosine , pressure overload , atrial natriuretic peptide , muscle hypertrophy , ventricle , phenylephrine , natriuretic peptide , adenosine receptor , fibrosis , receptor , heart failure , blood pressure , nitric oxide synthase , nitric oxide , cardiac hypertrophy , agonist

Endogenous adenosine can protect the overloaded heart against the development of hypertrophy and heart failure, but the contribution of A(1) receptors (A(1)R) and A(3) receptors (A(3)R) is not known.

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