Functional Impairment of Von Willebrand Factor in Hypertrophic Cardiomyopathy | Zendy

Thierry Le Tourneau | Zendy; Sophie Susen | Zendy; Claudine Caron | Zendy; A Millaire | Zendy; Sylvestre Maréchaux | Zendy; AnneSophie Polge | Zendy; André Vincentelli | Zendy; Frédéric Mouquet | Zendy; PierreVladimir Ennezat | Zendy; Nicolas Lamblin | Zendy; Pascal de Groote | Zendy; Éric Van Belle | Zendy; Ghislaine Deklunder | Zendy; Jenny Goudemand | Zendy; Christophe Bauters | Zendy; Brigitte Jude | Zendy

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Functional Impairment of Von Willebrand Factor in Hypertrophic Cardiomyopathy

Author(s) -

Thierry Le Tourneau,

Sophie Susen,

Claudine Caron,

A Millaire,

Sylvestre Maréchaux,

AnneSophie Polge,

André Vincentelli,

Frédéric Mouquet,

PierreVladimir Ennezat,

Nicolas Lamblin,

Pascal de Groote,

Éric Van Belle,

Ghislaine Deklunder,

Jenny Goudemand,

Christophe Bauters,

Brigitte Jude

Publication year - 2008

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.108.786681

Subject(s) - medicine , von willebrand factor , hypertrophic cardiomyopathy , cardiology , cardiomyopathy , platelet , endocrinology , heart failure

Hypertrophic obstructive cardiomyopathy submits blood to conditions of high shear stress. High shear stress impairs von Willebrand factor (VWF) and promotes abnormal bleeding in aortic stenosis. We sought to evaluate VWF impairment and its relationships to baseline or exercise obstruction in hypertrophic cardiomyopathy (HCM).

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