Impact of Statin Therapy on Central Aortic Pressures and Hemodynamics | Zendy

Bryan Williams | Zendy; Peter Lacy | Zendy; J. CRUICKSHANK | Zendy; David Collier | Zendy; Alun D. Hughes | Zendy; Alice Stanton | Zendy; Simon Thom | Zendy; H. Thurston | Zendy

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Impact of Statin Therapy on Central Aortic Pressures and Hemodynamics

Author(s) -

Bryan Williams,

Peter Lacy,

J. CRUICKSHANK,

David Collier,

Alun D. Hughes,

Alice Stanton,

Simon Thom,

H. Thurston

Publication year - 2008

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.108.785915

Subject(s) - medicine , blood pressure , atorvastatin , pulse pressure , cardiology , placebo , brachial artery , hemodynamics , aortic pressure , confidence interval , radial artery , pulse wave velocity , aorta , anesthesia , artery , alternative medicine , pathology

Statins reduce the risk of cardiovascular events in people with hypertension. This benefit could arise from a beneficial effect of statins on central aortic pressures and hemodynamics. The Conduit Artery Function Evaluation-Lipid-Lowering Arm (CAFE-LLA) study, an Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) substudy, investigated this hypothesis in a prospective placebo-controlled study of treated patients with hypertension.

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