Elevated Heat Shock Protein 60 Levels Are Associated With Higher Risk of Coronary Heart Disease in Chinese
Author(s) -
Xiaomin Zhang,
Meian He,
Longxian Cheng,
Ying Chen,
Li Zhou,
Hesong Zeng,
A. Graham Pockley,
Frank B. Hu,
Tangchun Wu
Publication year - 2008
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.108.781856
Subject(s) - medicine , hsp60 , myocardial infarction , quartile , pathogenesis , antibody , shock (circulatory) , diabetes mellitus , coronary heart disease , cardiology , heat shock protein , endocrinology , immunology , confidence interval , hsp70 , biochemistry , chemistry , gene
Although heat shock protein 60 (Hsp60) is implicated in the pathogenesis of atherosclerosis, its role in coronary heart disease (CHD) is uncertain. This study explored the influence of circulating Hsp60 on CHD in a large case-control study, as well as the impact of acute myocardial infarction on Hsp60 levels in a prospective study.
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