Presence of Older Thrombus Is an Independent Predictor of Long-Term Mortality in Patients With ST-Elevation Myocardial Infarction Treated With Thrombus Aspiration During Primary Percutaneous Coronary Intervention
Author(s) -
Miranda C.A. Kramer,
Allard C. van der Wal,
Karel T. Koch,
Johanna P.H.M. Ploegmakers,
René J. van der Schaaf,
José P.S. Henriques,
Jan Baan,
Saskia Z.H. Rittersma,
Marije M. Vis,
Jan J. Piek,
Jan G.P. Tijssen,
Robbert J. de Winter
Publication year - 2008
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.108.780734
Subject(s) - medicine , thrombus , percutaneous coronary intervention , myocardial infarction , hazard ratio , cardiology , confidence interval , surgery
Routine thrombus aspiration is frequently used during primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction to prevent distal embolization. Recently, evidence of clinical benefit was published. In 50% of the ST-elevation myocardial infarction patients with an onset of symptoms <12 hours before, thrombi were shown to be >1 day old. This observation illustrates that plaque rupture and coronary occlusion are significantly separated in time. In the present study, we correlate the presence of fresh versus older thrombus with long-term mortality.
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