Gene Transfer of Inducible Nitric Oxide Synthase Affords Cardioprotection by Upregulating Heme Oxygenase-1 Via a Nuclear Factor-κB-Dependent Pathway | Zendy

Qianhong Li | Zendy; Yiru Guo | Zendy; Qinghui Ou | Zendy; Chuan-Jue Cui | Zendy; Wen-Jian Wu | Zendy; Wei Tan | Zendy; Xiaoping Zhu | Zendy; Lilibeth Lanceta | Zendy; Santosh K. Sanganalmath | Zendy; Buddhadeb Dawn | Zendy; Ken Shinmura | Zendy; Gregg Rokosh | Zendy; Shuyan Wang | Zendy; Roberto Bolli | Zendy

Open Access

Gene Transfer of Inducible Nitric Oxide Synthase Affords Cardioprotection by Upregulating Heme Oxygenase-1 Via a Nuclear Factor-κB-Dependent Pathway

Author(s) -

Qianhong Li,

Yiru Guo,

Qinghui Ou,

Chuan-Jue Cui,

Wen-Jian Wu,

Wei Tan,

Xiaoping Zhu,

Lilibeth Lanceta,

Santosh K. Sanganalmath,

Buddhadeb Dawn,

Ken Shinmura,

Gregg Rokosh,

Shuyan Wang,

Roberto Bolli

Publication year - 2009

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.108.778688

Subject(s) - heme oxygenase , cardioprotection , nitric oxide synthase , medicine , heme , gene transfer , nitric oxide , microbiology and biotechnology , pharmacology , gene , biochemistry , enzyme , biology , ischemia

Although inducible nitric oxide synthase (iNOS) is known to impart powerful protection against myocardial infarction, the mechanism for this salubrious action remains unclear.

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