Early Diagnosis and Treatment of Atrioventricular Block in the Fetus Exposed to Maternal Anti-SSA/Ro-SSB/La Antibodies | Zendy

Azaria J.J.T. Rein | Zendy; Dror Mevorach | Zendy; Zeev Perles | Zendy; Sagui Gavri | Zendy; M. Nadjari | Zendy; Amiram Nir | Zendy; Uriel Elchalal | Zendy

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Early Diagnosis and Treatment of Atrioventricular Block in the Fetus Exposed to Maternal Anti-SSA/Ro-SSB/La Antibodies

Author(s) -

Azaria J.J.T. Rein,

Dror Mevorach,

Zeev Perles,

Sagui Gavri,

M. Nadjari,

Amiram Nir,

Uriel Elchalal

Publication year - 2009

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.108.773143

Subject(s) - medicine , fetus , gestation , in utero , gestational age , pregnancy , atrioventricular block , obstetrics , cardiology , genetics , biology

A fetus exposed to maternal anti-SSA/Ro or anti-SSB/La antibodies (or both) may develop complete atrioventricular block (AVB), which results in high prenatal and postnatal morbidity and mortality. Until recently, only high-grade AVB could be diagnosed in utero. The tissue velocity-based fetal kinetocardiogram (FKCG) enables accurate measurement of AV conduction time and diagnosis of low-grade AVB. In the present multicenter observational study, we used FKCG to detect first-degree AVB in fetuses at risk.

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