Endothelial Function Predicts Progression of Carotid Intima-Media Thickness | Zendy

Julian Halcox | Zendy; Ann E. Donald | Zendy; Elizabeth A. Ellins | Zendy; Daniel R. Witte | Zendy; Martin J. Shipley | Zendy; Eric J. Brunner | Zendy; Michael Marmot | Zendy; John Deanfield | Zendy

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Endothelial Function Predicts Progression of Carotid Intima-Media Thickness

Author(s) -

Julian Halcox,

Ann E. Donald,

Elizabeth A. Ellins,

Daniel R. Witte,

Martin J. Shipley,

Eric J. Brunner,

Michael Marmot,

John Deanfield

Publication year - 2009

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.108.765701

Subject(s) - medicine , framingham risk score , endothelial dysfunction , intima media thickness , cardiology , framingham heart study , prospective cohort study , brachial artery , diabetes mellitus , blood pressure , population , risk factor , disease , endocrinology , carotid arteries , environmental health

Endothelial dysfunction develops early and has been shown to predict the development of clinical complications of atherosclerosis. However, the relationship between early endothelial dysfunction and the progression of arterial disease in the general population is unknown. We investigated endothelial dysfunction, risk factors, and progression of carotid intima-media thickness (cIMT) in late-middle-aged individuals at low to intermediate cardiovascular risk in a prospective study between 1997 and 2005.

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