Corticosteroids for Recurrent Pericarditis
Author(s) -
Massimo Imazio,
Antonio Brucato,
Davide Cumetti,
Giovanni Brambilla,
Brunella Demichelis,
Silvia Ferro,
Silvia Maestroni,
Enrico Cecchi,
Riccardo Belli,
G. Palmieri,
Rita Trinchero
Publication year - 2008
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.107.761064
Subject(s) - medicine , prednisone , pericarditis , hazard ratio , confidence interval , retrospective cohort study , regimen , corticosteroid , surgery
Corticosteroid use is widespread in recurrent pericarditis, even if rarely indicated, and high doses (eg, prednisone 1.0 to 1.5 mg . kg(-1) . d(-1)) are generally recommended, although only weak evidence supports their use with possible severe side effects. The aim of this work was to compare side effects, recurrences and other complications, and hospitalizations of a low- versus high-dose regimen of prednisone for recurrent pericarditis.
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