Bioengineered Three-Layered Robust and Elastic Artery Using Hemodynamically-Equivalent Pulsatile Bioreactor | Zendy

Kiyotaka Iwasaki | Zendy; Koji Kojima | Zendy; Shohta Kodama | Zendy; Ana C. Paz | Zendy; Melody Chambers | Zendy; Mitsuo Umezu | Zendy; Charles A. Vacanti | Zendy

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Bioengineered Three-Layered Robust and Elastic Artery Using Hemodynamically-Equivalent Pulsatile Bioreactor

Author(s) -

Kiyotaka Iwasaki,

Koji Kojima,

Shohta Kodama,

Ana C. Paz,

Melody Chambers,

Mitsuo Umezu,

Charles A. Vacanti

Publication year - 2008

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.107.757369

Subject(s) - pulsatile flow , elastin , tissue engineering , biomedical engineering , lumen (anatomy) , bioreactor , internal elastic lamina , artery , medicine , biofabrication , anatomy , pathology , surgery , chemistry , organic chemistry

There is an essential demand for tissue engineered autologous small-diameter vascular graft, which can function in arterial high pressure and flow circulation. We investigated the potential to engineer a three-layered robust and elastic artery using a novel hemodynamically-equivalent pulsatile bioreactor.

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