Smoking Cessation Early in Pregnancy and Birth Weight, Length, Head Circumference, and Endothelial Nitric Oxide Synthase Activity in Umbilical and Chorionic Vessels | Zendy

Malene R. Andersen | Zendy; Ulf Simonsen | Zendy; Niels Uldbjerg | Zendy; Christian Aalkjær | Zendy; Steen Stender | Zendy

Open Access

Smoking Cessation Early in Pregnancy and Birth Weight, Length, Head Circumference, and Endothelial Nitric Oxide Synthase Activity in Umbilical and Chorionic Vessels

Author(s) -

Malene R. Andersen,

Ulf Simonsen,

Niels Uldbjerg,

Christian Aalkjær,

Steen Stender

Publication year - 2009

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.107.755769

Subject(s) - medicine , endothelial nitric oxide synthase , obstetrics , head circumference , pregnancy , nitric oxide , nitric oxide synthase , birth weight , smoking cessation , enos , pathology , biology , genetics

Reduced production of the vasodilator nitric oxide (NO) in fetal vessels in pregnant smokers may lower the blood flow to the fetus and result in lower birth weight, length, and head circumference. The present study measured endothelial NO synthase (eNOS) activity in fetal umbilical and chorionic vessels from nonsmokers, smokers, and ex-smokers and related the findings to the fetal outcome.

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