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Specific Jagged-1 Signal From Bone Marrow Microenvironment Is Required for Endothelial Progenitor Cell Development for Neovascularization
Author(s) -
SangMo Kwon,
Masamichi Eguchi,
Mika Wada,
Yo Iwami,
Katsuhito Hozumi,
Hideki Iwaguro,
Haruchika Masuda,
Atsuhiko Kawamoto,
Takayuki Asahara
Publication year - 2008
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.107.754978
Subject(s) - vasculogenesis , neovascularization , progenitor cell , medicine , bone marrow , notch signaling pathway , stromal cell , cancer research , microbiology and biotechnology , angiogenesis , endothelial progenitor cell , immunology , stem cell , biology , receptor
Despite accumulating evidence that proves the pivotal role of endothelial progenitor cells (EPCs) in ischemic neovascularization, the key signaling cascade that regulates functional EPC kinetics remains unclear.

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