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Increased High-Density Lipoprotein Cholesterol Predicts the Pioglitazone-Mediated Reduction of Carotid Intima-Media Thickness Progression in Patients With Type 2 Diabetes Mellitus
Author(s) -
Michael Davidson,
Peter Meyer,
Steven M. Haffner,
Steven B. Feinstein,
Ralph B. D’Agostino,
George T. Kondos,
Alfonso Pérez,
Zhen Chen,
Theodore Mazzone
Publication year - 2008
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.107.746610
Subject(s) - pioglitazone , medicine , endocrinology , glimepiride , intima media thickness , triglyceride , cholesterol , diabetes mellitus , apolipoprotein b , high density lipoprotein , insulin resistance , insulin , lipoprotein , body mass index , type 2 diabetes mellitus , type 2 diabetes , cardiology , carotid arteries
Measurement of carotid intima-media thickness (CIMT) has been validated as a measure of atherosclerosis and as a predictor of future cardiovascular events. Compared with glimepiride, pioglitazone has been shown to slow the progression of atherosclerosis measured by CIMT in patients with type 2 diabetes mellitus.

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