Inflammation, Oxidative Stress, and Repair Capacity of the Vascular Endothelium in Obstructive Sleep Apnea | Zendy

Sanja Jelić | Zendy; Margherita Padeletti | Zendy; Steven M. Kawut | Zendy; Christopher Higgins | Zendy; Stephen M. Canfield | Zendy; Duygu Onat | Zendy; P.C. Colombo | Zendy; Robert C. Basner | Zendy; Phillip Factor | Zendy; Thierry H. LeJemtel | Zendy

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Inflammation, Oxidative Stress, and Repair Capacity of the Vascular Endothelium in Obstructive Sleep Apnea

Author(s) -

Sanja Jelić,

Margherita Padeletti,

Steven M. Kawut,

Christopher Higgins,

Stephen M. Canfield,

Duygu Onat,

P.C. Colombo,

Robert C. Basner,

Phillip Factor,

Thierry H. LeJemtel

Publication year - 2008

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.107.741512

Subject(s) - medicine , oxidative stress , obstructive sleep apnea , endothelium , inflammation , cardiology , sleep apnea , sleep (system call) , computer science , operating system

Indirect evidence implicates endothelial dysfunction in the pathogenesis of vascular diseases associated with obstructive sleep apnea (OSA). We investigated directly whether dysfunction and inflammation occur in vivo in the vascular endothelium of patients with OSA. The effects of continuous positive airway pressure (CPAP) therapy on endothelial function and repair capacity were assessed.

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