Selective Vacuolar Degeneration in Dystrophin-Deficient Canine Purkinje Fibers Despite Preservation of Dystrophin-Associated Proteins With Overexpression of Dp71 | Zendy

Nobuyuki Urasawa | Zendy; Michiko Wada | Zendy; Noboru Machida | Zendy; Katsutoshi Yuasa | Zendy; Yoshiki Shimatsu | Zendy; Yoshito Wakao | Zendy; Shigeki Yuasa | Zendy; Toshiaki Sano | Zendy; Ikuya aka | Zendy; Akinori Nakamura | Zendy; Shin’ichi Takeda | Zendy

Open Access

Selective Vacuolar Degeneration in Dystrophin-Deficient Canine Purkinje Fibers Despite Preservation of Dystrophin-Associated Proteins With Overexpression of Dp71

Author(s) -

Nobuyuki Urasawa,

Michiko Wada,

Noboru Machida,

Katsutoshi Yuasa,

Yoshiki Shimatsu,

Yoshito Wakao,

Shigeki Yuasa,

Toshiaki Sano,

Ikuya aka,

Akinori Nakamura,

Shin’ichi Takeda

Publication year - 2008

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.107.739326

Subject(s) - dystrophin , sarcolemma , purkinje cell , purkinje fibers , duchenne muscular dystrophy , pathology , medicine , degeneration (medical) , desmin , muscular dystrophy , utrophin , microbiology and biotechnology , biology , cerebellum , myocyte , immunohistochemistry , electrophysiology , vimentin

Respiratory support therapy significantly improves life span in patients with Duchenne muscular dystrophy; cardiac-related fatalities, including lethal arrhythmias, then become a crucial issue. It is therefore important to more thoroughly understand cardiac involvement, especially pathology of the conduction system, in the larger Duchenne muscular dystrophy animal models such as dystrophic dogs.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research