Angiotensin-Converting Enzyme Inhibition Improves Vascular Function in Rheumatoid Arthritis | Zendy

Andreas J. Flammer | Zendy; Isabella Sudano | Zendy; Frank Hermann | Zendy; Steffen Gay | Zendy; Adrian Forster | Zendy; Michel Neidhart | Zendy; Peter Künzler | Zendy; Frank Enseleit | Zendy; Daniel Périat | Zendy; Matthias Hermann | Zendy; Juerg Nussberger | Zendy; Thomas F. Lüscher | Zendy; Roberto Corti | Zendy; Georg Noll | Zendy; Frank Ruschitzka | Zendy

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Angiotensin-Converting Enzyme Inhibition Improves Vascular Function in Rheumatoid Arthritis

Author(s) -

Andreas J. Flammer,

Isabella Sudano,

Frank Hermann,

Steffen Gay,

Adrian Forster,

Michel Neidhart,

Peter Künzler,

Frank Enseleit,

Daniel Périat,

Matthias Hermann,

Juerg Nussberger,

Thomas F. Lüscher,

Roberto Corti,

Georg Noll,

Frank Ruschitzka

Publication year - 2008

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.107.734384

Subject(s) - medicine , rheumatoid arthritis , angiotensin converting enzyme , angiotensin ii , arthritis , cardiology , receptor , blood pressure

The excess in cardiovascular risk in patients with rheumatoid arthritis provides a strong rationale for early therapeutical interventions. In view of the similarities between atherosclerosis and rheumatoid arthritis and the proven benefit of angiotensin-converting enzyme inhibitors in atherosclerotic vascular disease, it was the aim of the present study to delineate the impact of ramipril on endothelial function as well as on markers of inflammation and oxidative stress in patients with rheumatoid arthritis.

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