Cardiac Autonomic Dysfunction | Zendy

Andrea Baccarelli | Zendy; Patricia A. Cassano | Zendy; Augusto A. Litonjua | Zendy; Sung Kyun Park | Zendy; Helen Suh | Zendy; David Sparrow | Zendy; Pantel Vokonas | Zendy; Joel Schwartz | Zendy

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Cardiac Autonomic Dysfunction

Author(s) -

Andrea Baccarelli,

Patricia A. Cassano,

Augusto A. Litonjua,

Sung Kyun Park,

Helen Suh,

David Sparrow,

Pantel Vokonas,

Joel Schwartz

Publication year - 2008

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.107.726067

Subject(s) - methylenetetrahydrofolate reductase , medicine , heart rate variability , methionine , homocysteine , endocrinology , heart rate , genotype , blood pressure , biochemistry , gene , biology , amino acid

Particulate air pollution is associated with cardiovascular mortality and morbidity. To help identify mechanisms of action and protective/susceptibility factors, we evaluated whether the effect of particulate matter <2.5 mum in aerodynamic diameter (PM(2.5)) on heart rate variability was modified by dietary intakes of methyl nutrients (folate, vitamins B(6) and B(12), methionine) and related gene polymorphisms (C677T methylenetetrahydrofolate reductase [MTHFR] and C1420T cytoplasmic serine hydroxymethyltransferase [cSHMT]).

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