Leukocyte Integrin Mac-1 Promotes Acute Cardiac Allograft Rejection | Zendy

Koïchi Shimizu | Zendy; Peter Libby | Zendy; Rica Shubiki | Zendy; Masashi Sakuma | Zendy; Yunmei Wang | Zendy; Kenichi Asano | Zendy; Richard N. Mitchell | Zendy; Daniel I. Simon | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Leukocyte Integrin Mac-1 Promotes Acute Cardiac Allograft Rejection

Author(s) -

Koïchi Shimizu,

Peter Libby,

Rica Shubiki,

Masashi Sakuma,

Yunmei Wang,

Kenichi Asano,

Richard N. Mitchell,

Daniel I. Simon

Publication year - 2008

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.107.724310

Subject(s) - medicine , adoptive cell transfer , integrin alpha m , immunology , transplantation , cd18 , in vivo , t cell , immune system , biology , microbiology and biotechnology

In allograft rejection, recipient leukocytes and alloantibodies first target donor endothelial cells. Although the leukocyte integrin Mac-1 (alpha(Mbeta2), CD11b/CD18) facilitates cell-cell interactions among leukocytes and interactions between leukocytes and endothelial cells or platelets, its role in allograft survival and vasculopathy is incompletely defined.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research